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Semaglutide vs. Tirzepatide: how they differ

If you're considering a GLP-1 program, you'll see two names again and again: Semaglutide and Tirzepatide. Here's what each one is, in plain words, and how a physician helps you choose.

What they have in common

  • Both are taken once a week, as a small injection under the skin.
  • Both influence hormones involved in appetite regulation and metabolic signaling.
  • Both are used alongside nutrition and lifestyle changes, not instead of them.
  • Both require a prescription. At NADforWellness, a licensed California physician reviews your health answers before anything is prescribed.

How they differ

Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. It acts on one hormone pathway, GLP-1.

Tirzepatide belongs to a class known as GLP-1 and GIP receptor agonists. It acts on two hormone pathways, GLP-1 and GIP.

Semaglutide Tirzepatide
Medication class GLP-1 receptor agonist GLP-1 and GIP receptor agonist
How often Once a week Once a week
How it's taken Injection under the skin Injection under the skin
NADforWellness price From $249/month From $399/month

Which one is right for you?

That's a medical decision, and it depends on your health history. Choose the option that appeals to you when you take the quiz, and a licensed California physician reviews your answers to confirm it's appropriate before anything is prescribed. If it isn't right for you, we'll let you know, and you'll receive a full refund.

Dosing and price tiers

Both medications start at a lower dose that your provider may adjust over time. Higher doses have a higher monthly price, and we always ask for your OK before a higher price applies. Your provider makes every dose decision.

Questions?

Email support@nadforwellness.com. Real people answer.

Compounded medications are not FDA-approved. Prescription required; a licensed physician determines eligibility.

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